Manufacturing Equipment

Manufacturing equipment is a keystone to our quality. While many custom manufacturers boast of large capacity, Genzyme Pharmaceuticals prides itself on the flexibility and adaptability of its equipment to suit the short and long term needs of developing complex chemicals. Production capabilities range from small kilo to ton capacity, providing optimized value, cost considerations, and supply chain management for each customer’s position in the commercialization process.

The following manufacturing equipment is currently utilized in our Liestal facility:

General Manufacturing
For reactions between -100°C and +160°C:

For reactions up to 25 bar pressure:

For reactions between -100°C and +250°C:

Solid-Phase Peptide Synthesis
Up to 1,000 liter volume

Chromatography
200 to 300 liter flash chromatography column (glass)

Classified Clean Rooms
Class 100,000 (ISO class 8) and 10,000 (ISO class 7) clean rooms
Class 100 (ISO class 5) laminar air flow cabinets

Lyophilization
Lyophilizer for up to 25 kg of purified peptide solution in a Class 10,000 (ISO class 7) clean room
Various vacuum lyophilizers (for intermediates only) in a Class 100,000 (ISO class 8) clean room and in controlled rooms

Other Dryers in a Class 100,000 (ISO Class 8) clean room
Up to 1,000 liter stainless steel or enamel-coated vacuum dryer
Up to 1,000 liter plate, cone, stirring, filter dryers

HPLC Purification (closed handling) in a dedicated room:
Preparative HPLC columns of various sizes available
Up to 90cm (ht.) x 15cm (dia.)